Extracellular vesicles derived from Akkermansia muciniphila promote placentation and mitigate preeclampsia in a mouse model

Extracellular vesicles derived from Akkermansia muciniphila promote placentation and mitigate preeclampsia in a mouse model

Abstract Preeclampsia (PE) is a multisystem disorder with high maternal morbidity and mortality rates. Currently, no practical therapeutic approach is available to prevent PE progression, except for early delivery. Gut dysbiosis is associated with PE development. Previous data showed that the abunda...

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Bibliographic Details
Main Authors: Yun Chen, Zihao Ou, Menglan Pang, Zixin Tao, Xifen Zheng, Zhipeng Huang, Dongni Wen, Qianbei Li, Ruisi Zhou, Peng Chen, Bo Situ, Chao Sheng, Yingying Huang, Xiaojing Yue, Lei Zheng, Liping Huang
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Journal of Extracellular Vesicles
Subjects:
Akkermansia muciniphila
extracellular vesicles
preeclampsia
placentation
EGFR–PI3K–AKT pathway
Online Access:https://doi.org/10.1002/jev2.12328

Internet

https://doi.org/10.1002/jev2.12328

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