α-granule biogenesis: from disease to discovery

Platelets are critical to hemostasis and thrombosis. Upon detecting injury, platelets show a range of responses including the release of protein cargo from α-granules. This cargo is synthesized by platelet precursor megakaryocytes or endocytosed by megakaryocytes and/or platelets. Insights into α-gr...

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Bibliographic Details
Main Authors: Chang Hua Chen, Richard W. Lo, Denisa Urban, Fred G. Pluthero, Walter H. A. Kahr
Format: Article
Language:English
Published: Taylor & Francis Group 2017-02-01
Series:Platelets
Subjects:
Online Access:http://dx.doi.org/10.1080/09537104.2017.1280599