DGK α and ζ Activities Control TH1 and TH17 Cell Differentiation

DGK α and ζ Activities Control TH1 and TH17 Cell Differentiation

CD4+ T helper (TH) cells are critical for protective adaptive immunity against pathogens, and they also contribute to the pathogenesis of autoimmune diseases. How TH differentiation is regulated by the TCR's downstream signaling is still poorly understood. We describe here that diacylglycerol k...

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Bibliographic Details
Main Authors: Jialong Yang, Hong-Xia Wang, Jinhai Xie, Lei Li, Jinli Wang, Edwin C. K. Wan, Xiao-Ping Zhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
Th differentiation
Th17
Th1
mTOR
DGK
airway inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.03048/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.03048/full

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