Novel mutations in genes of the IL-12/IFN-γ axis cause susceptibility to tuberculosis
Background: The IL-12/23/ISG15-IFN-γ pathway is the main immunological pathway for controlling intra-macrophagic microorganisms such as Mycobacteria, Salmonella, and Leishmania spp. Consequently, upon mutations in genes of the IL-12/23/ISG15-IFN-γ pathway cause increased susceptibility to intra-macr...
Автори: | , , , , , , , , , |
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Формат: | Стаття |
Мова: | English |
Опубліковано: |
Elsevier
2023-09-01
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Серія: | Journal of Infection and Public Health |
Предмети: | |
Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S1876034123002101 |