Cells Responding to Closely Related Cholesterol-Dependent Cytolysins Release Extracellular Vesicles with a Common Proteomic Content Including Membrane Repair Proteins

Cells Responding to Closely Related Cholesterol-Dependent Cytolysins Release Extracellular Vesicles with a Common Proteomic Content Including Membrane Repair Proteins

The plasma membrane (PM) protects cells from extracellular threats and supports cellular homeostasis. Some pathogens produce pore-forming toxins (PFTs) that disrupt PM integrity by forming transmembrane pores. High PFT concentrations cause massive damage leading to cell death and facilitating infect...

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Bibliographic Details
Main Authors: Sara Alves, Joana M. Pereira, Rupert L. Mayer, Alexandre D. A. Gonçalves, Francis Impens, Didier Cabanes, Sandra Sousa
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Toxins
Subjects:
pore-forming toxins
plasma membrane repair
shedding
extracellular vesicles
listeriolysin O
pneumolysin
Online Access:https://www.mdpi.com/2072-6651/15/1/4

Internet

https://www.mdpi.com/2072-6651/15/1/4

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