Mechanism of Allosteric Modulation of the Cys-loop Receptors
The cys-loop receptor family is a major family of neurotransmitter-operated ion channels. They play important roles in fast synaptic transmission, controlling neuronal excitability, and brain function. These receptors are allosteric proteins, in that binding of a neurotransmitter to its binding site...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2010-08-01
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Series: | Pharmaceuticals |
Subjects: | |
Online Access: | http://www.mdpi.com/1424-8247/3/8/2592/ |