Enhanced expression of miR-20a driven by nanog exacerbated the degradation of extracellular matrix in thoracic aortic dissection

Enhanced expression of miR-20a driven by nanog exacerbated the degradation of extracellular matrix in thoracic aortic dissection

Thoracic aortic dissection (TAD) is a life-threatening vascular disease manifested as intramural bleeding in the medial layers of the thoracic aorta. The key histopathologic feature of TAD is medial degeneration, characterized by depletion of vascular smooth muscle cells (VSMCs) and degradation of e...

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Bibliographic Details
Main Authors: Zhao An, Yangyong Sun, Xiaodong Yang, Jingwen Zhou, Yongchao Yu, Boyao Zhang, Zhiyun Xu, Yuming Zhu, Guokun Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-12-01
Series:Non-coding RNA Research
Subjects:
Thoracic aortic dissection
Extracellular matrix degradation
miR-20a
Tissue inhibitors of metalloproteinase 2
Nanog
Online Access:http://www.sciencedirect.com/science/article/pii/S2468054024000933

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http://www.sciencedirect.com/science/article/pii/S2468054024000933

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