Impaired macrophage and memory T-cell responses to Bacillus Calmette-Guerin nonpolar lipid extract

Impaired macrophage and memory T-cell responses to Bacillus Calmette-Guerin nonpolar lipid extract

IntroductionThe attenuation of BCG has led to the loss of not only immunogenic proteins but also lipid antigens.MethodsThus, we compared the macrophage and T-cell responses to nonpolar lipid extracts harvested from BCG and Mycobacterium tuberculosis (Mtb) to better understand the role of BCG lipids...

Full description

Bibliographic Details
Main Authors: Alice Sarno, Avelina Leite, Carlos Augusto, Igor Muller, Luanna de Ângelis, Lilian Pimentel, Adriano Queiroz, Sergio Arruda
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
Bacillus Calmette-Guerin
Mycobacterium tuberculosis
nonpolar lipid extracts
macrophage gene expression
memory T-cell responses
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1263352/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1263352/full

Similar Items