Impaired macrophage and memory T-cell responses to Bacillus Calmette-Guerin nonpolar lipid extract
IntroductionThe attenuation of BCG has led to the loss of not only immunogenic proteins but also lipid antigens.MethodsThus, we compared the macrophage and T-cell responses to nonpolar lipid extracts harvested from BCG and Mycobacterium tuberculosis (Mtb) to better understand the role of BCG lipids...
Main Authors: | Alice Sarno, Avelina Leite, Carlos Augusto, Igor Muller, Luanna de Ângelis, Lilian Pimentel, Adriano Queiroz, Sergio Arruda |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2024-01-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1263352/full |
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