A multi-dimensional approach to unravel the intricacies of lactylation related signature for prognostic and therapeutic insight in colorectal cancer

A multi-dimensional approach to unravel the intricacies of lactylation related signature for prognostic and therapeutic insight in colorectal cancer

Abstract Background Lactylation, a novel contributor to post-translational protein modifications, exhibits dysregulation across various tumors. Nevertheless, its intricate involvement in colorectal carcinoma, particularly for non-histone lactylation and its intersection with metabolism and immune ev...

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Bibliographic Details
Main Authors: Huixia Huang, Keji Chen, Yifei Zhu, Zijuan Hu, Yaxian Wang, Jiayu Chen, Yuxue Li, Dawei Li, Ping Wei
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Translational Medicine
Subjects:
Lactylation
Colorectal cancer
Tumor microenvironment
Immunotherapy
Tumor mutation burden
Drug sensitivity
Online Access:https://doi.org/10.1186/s12967-024-04955-9

Internet

https://doi.org/10.1186/s12967-024-04955-9

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