Understanding the Mechanism of Dysglycemia in a Fanconi-Bickel Syndrome Patient

Understanding the Mechanism of Dysglycemia in a Fanconi-Bickel Syndrome Patient

Fanconi–Bickel Syndrome (FBS) is a rare disorder of carbohydrate metabolism that is characterized mainly by the accumulation of glycogen in the liver and kidney. It is inherited as an autosomal recessive disorder caused by mutations in the SLC2A2 gene, which encodes for GLUT2. Patients with FBS have...

Full description

Bibliographic Details
Main Authors: Sanaa Sharari, Mustapha Aouida, Idris Mohammed, Basma Haris, Ajaz Ahmad Bhat, Iman Hawari, Sabah Nisar, Igor Pavlovski, Kabir H. Biswas, Najeeb Syed, Selma Maacha, Jean-Charles Grivel, Maryam Saifaldeen, Johan Ericsson, Khalid Hussain
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Endocrinology
Subjects:
Fanconi-Bickel syndrome (FBS)
dysglycemia
glucose transporter 2 (GLUT2)
clustered regularly interspaced short palindromic repeats (CRISPR)- Cas9
sodium-glucose transport protein 2 (SGLT2)
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.841788/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.841788/full

Similar Items