Reduced decline of lung diffusing capacity in COPD patients with diabetes and metformin treatment

Abstract We studied whether in patients with COPD the use of metformin for diabetes treatment was linked to a pattern of lung function decline consistent with the hypothesis of anti-aging effects of metformin. Patients of GOLD grades 1–4 of the COSYCONET cohort with follow-up data of up to 4.5 y wer...

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Bibliographic Details
Main Authors: Kathrin Kahnert, Stefan Andreas, Christina Kellerer, Johanna I. Lutter, Tanja Lucke, Önder Yildirim, Mareike Lehmann, Jochen Seissler, Jürgen Behr, Marion Frankenberger, Robert Bals, Henrik Watz, Tobias Welte, Franziska C. Trudzinski, Claus F. Vogelmeier, Peter Alter, Rudolf A. Jörres, COSYCONET Study Group
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-05276-x