Alteration in the mRNA expression of genes associated with gastrointestinal permeability and ileal TNF-α secretion due to the exposure of silver nanoparticles in Sprague–Dawley rats

Alteration in the mRNA expression of genes associated with gastrointestinal permeability and ileal TNF-α secretion due to the exposure of silver nanoparticles in Sprague–Dawley rats

Abstract Background Silver ions from silver nanoparticles (AgNP) or AgNPs themselves itself that are ingested from consumer health care products or indirectly from absorbed food contact material can interact with the gastrointestinal tract (GIT). The permeability of the GIT is strictly regulated to...

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Bibliographic Details
Main Authors: Sarah E. Orr, Kuppan Gokulan, Mary Boudreau, Carl E. Cerniglia, Sangeeta Khare
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Journal of Nanobiotechnology
Subjects:
Silver nanoparticles
Gastrointestinal toxicity
Intestinal permeability
Claudin
Tight junctions
Online Access:http://link.springer.com/article/10.1186/s12951-019-0499-6

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http://link.springer.com/article/10.1186/s12951-019-0499-6

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