Modeling critical dosing strategies for stromal-induced resistance to cancer therapy

Abstract Complex interactions between stromal cells, tumor cells and therapies can influence environmental factors that in turn impact anticancer treatment efficacy. Disentangling these phenomena is critical for understanding treatment response and designing effective dosing strategies. We propose a...

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Bibliographic Details
Main Authors: Anna K. Kraut, Colleen M. Garvey, Carly Strelez, Shannon M. Mumenthaler, Jasmine Foo
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-025-00495-0