An Alternatively Spliced Variant of METTL3 Mediates Tumor Suppression in Hepatocellular Carcinoma

An Alternatively Spliced Variant of METTL3 Mediates Tumor Suppression in Hepatocellular Carcinoma

Many post-transcriptional mRNA processing steps play crucial roles in tumorigenesis and the progression of cancers, such as N6-methyladenosine (m<sup>6</sup>A) modification and alternative splicing. Upregulation of methyltransferase-like 3 (METTL3), the catalytic core of the m<sup>...

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Bibliographic Details
Main Authors: Rui-Yao Xu, Zhan Ding, Qing Zhao, Tiao-Ying Ke, Shu Chen, Xing-Yu Wang, Yao-Yun Wang, Meng-Fei Sheng, Wei Wang, Ni Long, Yu-Xian Shen, Yong-Zhen Xu, Wei Shao
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Genes
Subjects:
METTL3
splice variants
RNA m<sup>6</sup>A
hepatocellular carcinoma
tumor suppressor
Online Access:https://www.mdpi.com/2073-4425/13/4/669

Internet

https://www.mdpi.com/2073-4425/13/4/669

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