Cytoskeleton Protein EB3 Contributes to Dendritic Spines Enlargement and Enhances Their Resilience to Toxic Effects of Beta-Amyloid

Cytoskeleton Protein EB3 Contributes to Dendritic Spines Enlargement and Enhances Their Resilience to Toxic Effects of Beta-Amyloid

EB3 protein is expressed abundantly in the nervous system and transiently enters the dendritic spines at the tip of the growing microtubule, which leads to spine enlargement. Nevertheless, the role of dynamic microtubules, and particularly EB3 protein, in synapse function is still elusive. By manipu...

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Bibliographic Details
Main Authors: Ekaterina Pchitskaya, Anastasiya Rakovskaya, Margarita Chigray, Ilya Bezprozvanny
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
dendritic spines
neuronal morphology
EB3
end-binding protein
PSD95
Synapsin CaMKII
Online Access:https://www.mdpi.com/1422-0067/23/4/2274

Internet

https://www.mdpi.com/1422-0067/23/4/2274

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