Dopamine D3 receptor and GSK3β signaling mediate deficits in novel object recognition memory within dopamine transporter knockdown mice

Abstract Background Over-stimulation of dopamine signaling is thought to underlie the pathophysiology of a list of mental disorders, such as psychosis, mania and attention-deficit/hyperactivity disorder. These disorders are frequently associated with cognitive deficits in attention or learning and m...

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Bibliographic Details
Main Authors: Pi-Kai Chang, Jung Chu, Ya-Ting Tsai, Yan-Heng Lai, Jin-Chung Chen
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Biomedical Science
Subjects:
Online Access:https://doi.org/10.1186/s12929-019-0613-y