A one month high fat diet disrupts the gut microbiome and integrity of the colon inducing adiposity and behavioral despair in male Sprague Dawley rats

A one month high fat diet disrupts the gut microbiome and integrity of the colon inducing adiposity and behavioral despair in male Sprague Dawley rats

High-fat diet (HFD) is associated with gut microbiome dysfunction and mental disorders. However, the time-dependence as to when this occurs is unclear. We hypothesized that a short-term HFD causes colonic tissue integrity changes resulting in behavioral changes. Rats were fed HFD or low-fat diet (LF...

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Bibliographic Details
Main Authors: Gladys Chompre, Lubriel Sambolin, Myrella L. Cruz, Rafael Sanchez, Yarelis Rodriguez, Ronald E. Rodríguez-Santiago, Yasuhiro Yamamura, Caroline B. Appleyard
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Heliyon
Subjects:
Gut microbiome
Gut integrity
Claudin-5
Bacteriodes
Tight junction proteins
S24-7
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022024823

Internet

http://www.sciencedirect.com/science/article/pii/S2405844022024823

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