Opposite reactivity of meningeal versus cortical microvessels to the nitric oxide donor glyceryl trinitrate evaluated in vivo with two-photon imaging.

Opposite reactivity of meningeal versus cortical microvessels to the nitric oxide donor glyceryl trinitrate evaluated in vivo with two-photon imaging.

Vascular changes underlying headache in migraine patients induced by Glyceryl trinitrate (GTN) were previously studied with various imaging techniques. Despite the long history of medical and experimental use of GTN, its effects on the brain vasculature are still poorly understood presumably due to...

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Bibliographic Details
Main Authors: Evgeny Pryazhnikov, Mikhail Kislin, Marina Tibeykina, Dmytro Toptunov, Anna Ptukha, Artem Shatillo, Olli Gröhn, Rashid Giniatullin, Leonard Khiroug
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3938546?pdf=render

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http://europepmc.org/articles/PMC3938546?pdf=render

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