Transcription factor clusters regulate genes in eukaryotic cells

Transcription factor clusters regulate genes in eukaryotic cells

Transcription is regulated through binding factors to gene promoters to activate or repress expression, however, the mechanisms by which factors find targets remain unclear. Using single-molecule fluorescence microscopy, we determined in vivo stoichiometry and spatiotemporal dynamics of a GFP tagged...

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Bibliographic Details
Main Authors: Adam JM Wollman, Sviatlana Shashkova, Erik G Hedlund, Rosmarie Friemann, Stefan Hohmann, Mark C Leake
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-08-01
Series:eLife
Subjects:
gene expression
transcription factors
single-molecule
super-resolution
cell signaling
Online Access:https://elifesciences.org/articles/27451

Internet

https://elifesciences.org/articles/27451

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