Moxibustion improves hypothalamus Aqp4 polarization in APP/PS1 mice: Evidence from spatial transcriptomics

Moxibustion improves hypothalamus Aqp4 polarization in APP/PS1 mice: Evidence from spatial transcriptomics

Aquaporin-4 (AQP4) is highly polarized to perivascular astrocytic endfeet. Loss of AQP4 polarization is associated with many diseases. In Alzheimer’s disease (AD), AQP4 loses its normal location and thus reduces the clearance of amyloid-β plaques and tau protein. Clinical and experimental studies sh...

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Bibliographic Details
Main Authors: Shuqing Liu, Hongying Li, Yuan Shen, Weikang Zhu, Yong Wang, Junmeng Wang, Ning Zhang, Chenyu Li, Lushuang Xie, Qiaofeng Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
moxibustion
Alzheimer’s disease
spatial transcriptomics
aquaporin-4
mitochondrial respiratory chain
hypothalamus
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1069155/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2023.1069155/full

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