Zinc Chelation Specifically Inhibits Early Stages of Dengue Virus Replication by Activation of NF-κB and Induction of Antiviral Response in Epithelial Cells

Zinc Chelation Specifically Inhibits Early Stages of Dengue Virus Replication by Activation of NF-κB and Induction of Antiviral Response in Epithelial Cells

Zinc is an essential micronutrient which regulates diverse physiological functions and has been shown to play a crucial role in viral infections. Zinc has a necessary role in the replication of many viruses, however, antiviral action of zinc has also been demonstrated in in vitro infection models mo...

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Bibliographic Details
Main Authors: Meenakshi Kar, Naseem Ahmed Khan, Aleksha Panwar, Sachendra S. Bais, Soumen Basak, Renu Goel, Shailaja Sopory, Guruprasad R. Medigeshi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
dengue virus
zinc
rotavirus
epithelial cells
NF-kappaB
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02347/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02347/full

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