A genetic labeling system to study dendritic spine development in zebrafish models of neurodevelopmental disorders

Dendritic spines are the principal site of excitatory synapse formation in the human brain. Several neurodevelopmental disorders cause spines to develop abnormally, resulting in altered spine number and morphology. Although spine development has been thoroughly characterized in the mammalian brain,...

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Bibliographic Details
Main Authors: Elisabeth C. DeMarco, George R. Stoner, Estuardo Robles
Format: Article
Language:English
Published: The Company of Biologists 2022-08-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/15/8/dmm049507