Upregulation of miR-345-5p suppresses cell growth of lung adenocarcinoma by regulating ras homolog family member A (RhoA) and Rho/Rho associated protein kinase (Rho/ROCK) pathway

Abstract. Background:. Microribose nucleic acids (miRNAs) are implicated in the progression of lung adenocarcinoma. MicroRNA-345-5p (miR-345-5p) is a recently identified anti-oncogene in some human cancers, but its functional role and possible molecular mechanism in lung adenocarcinoma remain unknow...

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Bibliographic Details
Main Authors: Qiao-Yun Zhou, Shu-Yu Gui, Peng Zhang, Mei Wang, Pei-Fang Wei
Format: Article
Language:English
Published: Wolters Kluwer 2021-11-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000001804