New 6′-Amino-5′-cyano-2-oxo-1,2-dihydro-1′<i>H</i>-spiro[indole-3,4′-pyridine]-3′-carboxamides: Synthesis, Reactions, Molecular Docking Studies and Biological Activity

The purpose of this work was to prepare new isatin- and monothiomalondiamide-based indole derivatives, as well as to study the properties of the new compounds. The four-component reaction of 5-R-isatins (R = H, CH<sub>3</sub>), malononitrile, monothiomalonamide (3-amino-3-thioxo- propana...

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Bibliographic Details
Main Authors: Victor V. Dotsenko, Nawras T. Jassim, Azamat Z. Temerdashev, Zainab R. Abdul-Hussein, Nicolai A. Aksenov, Inna V. Aksenova
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/7/3161