Transcriptome-wide m6A methylome analysis uncovered the changes of m6A modification in oral pre-malignant cells compared with normal oral epithelial cells

Transcriptome-wide m6A methylome analysis uncovered the changes of m6A modification in oral pre-malignant cells compared with normal oral epithelial cells

As the most common post-transcriptional RNA modification, m6A methylation extensively regulates the structure and function of RNA. The dynamic and reversible modification of m6A is coordinated by m6A writers and erasers. m6A reader proteins recognize m6A modification on RNA, mediating different down...

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Bibliographic Details
Main Authors: Xun Chen, Liutao Chen, Yuquan Tang, Yi He, Kuangwu Pan, Linyu Yuan, Weihong Xie, Shangwu Chen, Wei Zhao, Dongsheng Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
Subjects:
m6A modification
m6A regulatory genes
MeRIP sequencing
precancerous cells
dysplastic oral keratinocyte (DOK)
human oral epithelial cell (HOEC)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.939449/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.939449/full

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