Bbvac: A Live Vaccine Candidate That Provides Long-Lasting Anamnestic and Th17-Mediated Immunity against the Three Classical Bordetella spp.

ABSTRACT Acute pathogens such as Bordetella pertussis can cause severe disease but are ultimately cleared by the immune response. This has led to the accepted paradigm that convalescent immunity is optimal and therefore broadly accepted as the “gold standard” against which vaccine candidates should...

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Bibliographic Details
Main Authors: Monica C. Gestal, Laura K. Howard, Kalyan K. Dewan, Eric T. Harvill
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msphere.00892-21