Iron Overload, Oxidative Stress, and Ferroptosis in the Failing Heart and Liver

Iron accumulation is a key mediator of several cytotoxic mechanisms leading to the impairment of redox homeostasis and cellular death. Iron overload is often associated with haematological diseases which require regular blood transfusion/phlebotomy, and it represents a common complication in thalass...

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Bibliographic Details
Main Authors: Daniele Mancardi, Mariarosa Mezzanotte, Elisa Arrigo, Alice Barinotti, Antonella Roetto
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/10/12/1864