The Many Facets of Therapy Resistance and Tumor Recurrence in Glioblastoma

The Many Facets of Therapy Resistance and Tumor Recurrence in Glioblastoma

Glioblastoma (GBM) is the most lethal type of primary brain cancer. Standard care using chemo- and radio-therapy modestly increases the overall survival of patients; however, recurrence is inevitable, due to treatment resistance and lack of response to targeted therapies. GBM therapy resistance has...

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Bibliographic Details
Main Authors: Anshika Goenka, Deanna Tiek, Xiao Song, Tianzhi Huang, Bo Hu, Shi-Yuan Cheng
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
glioblastoma
resistance
recurrence
tumor heterogeneity
hypermutation
metabolism
Online Access:https://www.mdpi.com/2073-4409/10/3/484

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https://www.mdpi.com/2073-4409/10/3/484

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