The gut microbiota metabolite urolithin A inhibits NF-κB activation in LPS stimulated BMDMs

Abstract Inflammation is a natural defense process of the innate immune system, associated with the release of proinflammatory cytokines such as interleukin-1β, interleukin-6, interleukin-12 and TNFα; and enzymes including iNOS through the activation and nuclear translocation of NF-κB p65 due to the...

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Bibliographic Details
Main Authors: Khalid N. M. Abdelazeem, M. Zaher Kalo, Sandra Beer-Hammer, Florian Lang
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86514-6