Cytosolic Cadherin 4 promotes angiogenesis and metastasis in papillary thyroid cancer by suppressing the ubiquitination/degradation of β-catenin

Cytosolic Cadherin 4 promotes angiogenesis and metastasis in papillary thyroid cancer by suppressing the ubiquitination/degradation of β-catenin

Abstract Background Although the long-term prognosis of papillary thyroid cancer (PTC) is favorable, distant metastasis significantly compromises the prognosis and quality of life for patients with PTC. The Cadherin family plays a pivotal role in tumor metastasis; however, the involvement of Cadheri...

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Bibliographic Details
Main Authors: Luyao Wu, Jian Xiao, Dandan Yi, Haoran Ding, Ru Wang, Zehua Duan, Zhijian Liu, Xianbiao Shi, Meiping Shen, Jianfeng Sang
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Translational Medicine
Subjects:
Papillary thyroid cancer
Cadherin 4
β-catenin
Ubiquitination
Metastasis
Online Access:https://doi.org/10.1186/s12967-024-05012-1

Internet

https://doi.org/10.1186/s12967-024-05012-1

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