A Cationic Amphipathic Tilapia Piscidin 4 Peptide-Based Antimicrobial Formulation Promotes Eradication of Bacterial Vaginosis-Associated Bacterial Biofilms

A Cationic Amphipathic Tilapia Piscidin 4 Peptide-Based Antimicrobial Formulation Promotes Eradication of Bacterial Vaginosis-Associated Bacterial Biofilms

Bacterial vaginosis (BV) is prevalent among women of reproductive age and has a high rate of recurrence, which can be largely attributed to ineffective BV biofilm eradication by current first-line antibiotics. In this study, we report that the Nile tilapia piscidin 4 (TP4) exhibits broad-spectrum an...

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Bibliographic Details
Main Authors: Wen-Chun Lin, Yun-Ru Chen, Chi-Mu Chuang, Jyh-Yih Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Microbiology
Subjects:
bacterial vaginosis
polymicrobial biofilm
vaginal microbicide formulation
amphipathic antimicrobial peptides
Nile tilapia piscidin 4
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.806654/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.806654/full

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