Inhibition of AEBP1 predisposes cisplatin-resistant oral cancer cells to ferroptosis

Abstract Background Studies have shown that excessive iron can lead to an increased incidence of cancer. The role of adipocyte enhancer-binding protein 1 (AEBP1) on ferroptosis is unknown. Thus, we explored the effect of AEBP1 silencing in regulation of ferroptosis in cisplatin-resistant oral cancer...

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Bibliographic Details
Main Authors: Qianwen Zhou, Xiaoqi Wang, Yingxue Zhang, Lie Wang, Zhijun Chen
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Oral Health
Subjects:
Online Access:https://doi.org/10.1186/s12903-022-02503-9