Gene, cell type, and drug prioritization analysis suggest genetic basis for the utility of diuretics in treating Alzheimer disease

Gene, cell type, and drug prioritization analysis suggest genetic basis for the utility of diuretics in treating Alzheimer disease

Summary: We introduce a user-friendly tool for risk gene, cell type, and drug prioritization for complex traits: GCDPipe. It uses gene-level GWAS-derived data and gene expression data to train a model for the identification of disease risk genes and relevant cell types. Gene prioritization informati...

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Bibliographic Details
Main Authors: Daria Pinakhina, Alexander Loboda, Alexey Sergushichev, Mykyta Artomov
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:HGG Advances
Subjects:
Gene prioritization
GWAS
Machine learning
GCDPipe
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247723000350

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http://www.sciencedirect.com/science/article/pii/S2666247723000350

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