Early antidepressant treatment response prediction in major depression using clinical and TPH2 DNA methylation features based on machine learning approaches

Early antidepressant treatment response prediction in major depression using clinical and TPH2 DNA methylation features based on machine learning approaches

Abstract Objective To identify DNA methylation and clinical features, and to construct machine learning classifiers to assign the patients with major depressive disorder (MDD) into responders and non-responders after a 2-week treatment into responders and non-responders. Method Han Chinese patients...

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Bibliographic Details
Main Authors: Bingwei Chen, Zhigang Jiao, Tian Shen, Ru Fan, Yuqi Chen, Zhi Xu
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Psychiatry
Subjects:
Major depressive disorder
TPH2
CpGs
Early antidepressant treatment response
Machine learning
Online Access:https://doi.org/10.1186/s12888-023-04791-z

Internet

https://doi.org/10.1186/s12888-023-04791-z

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