DA-9805, a Herbal Mixture, Restores Motor Manifestations in 6-Hydroxydopamine-induced Parkinson’s Disease Mouse Model by Regulating Striatal Dopamine and Acetylcholine Levels

DA-9805, a Herbal Mixture, Restores Motor Manifestations in 6-Hydroxydopamine-induced Parkinson’s Disease Mouse Model by Regulating Striatal Dopamine and Acetylcholine Levels

Loss of dopamine (DA) is one of the primary features of Parkinson’s disease (PD); however, imbalances of non-dopaminergic neurotransmitters significantly contribute to the disabilities noted in advanced PD patients. DA-9805 is the ethanolic extraction of the root bark of Paeonia × suffruticosa Andre...

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Bibliographic Details
Main Authors: Eugene Huh, Youngji Kwon, Jin Gyu Choi, Myung Gyu Lim, Jin Seok Jeong, Ah Yeon Park, Jeong Hee Kim, Youngmi Kim Pak, Seon-Pyo Hong, Myung Sook Oh
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
DA-9805
Parkinson’s disease
striatal neurotransmission
dopamine
acetylcholine
homeostasis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.903664/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.903664/full

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