Changes in pNFH Levels in Cerebrospinal Fluid and Motor Evolution after the Loading Dose with Nusinersen in Different Types of Spinal Muscular Atrophy

Changes in pNFH Levels in Cerebrospinal Fluid and Motor Evolution after the Loading Dose with Nusinersen in Different Types of Spinal Muscular Atrophy

<i>Aim and Objectives:</i> The objective of our retrospective study was to investigate the changes in pNFH levels in cerebrospinal fluid, which is a reliable marker of neuronal damage, after the loading dose of nusinersen in different types of spinal muscular atrophy. <i>Materials...

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Bibliographic Details
Main Authors: Mihaela Badina, Gabriel Cristian Bejan, Corina Sporea, Liliana Padure, Andrada Mirea, Madalina-Cristina Leanca, Mihaela Axente, Florin Petru Grigoras, Mihaela Bejan, Elena-Silvia Shelby, Elena Neagu, Daniela Adriana Ion
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Medicina
Subjects:
spinal muscular atrophy
neurodegenerative disease
neurofilaments
cerebrospinal fluid
pNFH
nusinersen
Online Access:https://www.mdpi.com/1648-9144/59/7/1244

Internet

https://www.mdpi.com/1648-9144/59/7/1244

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