PCV2 targets cGAS to inhibit type I interferon induction to promote other DNA virus infection.

PCV2 targets cGAS to inhibit type I interferon induction to promote other DNA virus infection.

Viruses use diverse strategies to impair the antiviral immunity of host in order to promote infection and pathogenesis. Herein, we found that PCV2 infection promotes the infection of DNA viruses through inhibiting IFN-β induction in vivo and in vitro. In the early phase of infection, PCV2 promotes t...

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Bibliographic Details
Main Authors: Zhenyu Wang, Jing Chen, Xingchen Wu, Dan Ma, Xiaohua Zhang, Ruizhen Li, Cong Han, Haixin Liu, Xiangrui Yin, Qian Du, Dewen Tong, Yong Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009940

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https://doi.org/10.1371/journal.ppat.1009940

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