Evaluation of the Formulation Parameter-Dependent Redispersibility of API Nanoparticles from Fluid Bed Granules

Evaluation of the Formulation Parameter-Dependent Redispersibility of API Nanoparticles from Fluid Bed Granules

The production of nanosuspensions of poorly soluble active pharmaceutical ingredients (API) is a popular technique to counteract challenges regarding bioavailability of such active substances. A subsequent drying of the nanosuspensions is advantageous to improve the long-term stability and the furth...

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Bibliographic Details
Main Authors: Martin Wewers, Jan Henrik Finke, Stefan Czyz, Bernard Van Eerdenbrugh, Edgar John, Guido Büch, Michael Juhnke, Heike Bunjes, Arno Kwade
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceutics
Subjects:
wet media milling
nanosuspensions
fluidized bed granulation
redispersibility
formulation parameters
Online Access:https://www.mdpi.com/1999-4923/14/8/1688

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https://www.mdpi.com/1999-4923/14/8/1688

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