IL-1β and TNF-α play an important role in modulating the risk of periodontitis and Alzheimer’s disease

Abstract Background Systemic activation of the immune system can exert detrimental effects on the central nervous system. Periodontitis, a chronic disease of the oral cavity, is a common source of systemic inflammation. Neuroinflammation might be a result of this to accelerate progressive deteriorat...

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Bibliographic Details
Main Authors: Rachel Pei-Hsuan Wang, Jianpan Huang, Kannie Wai Yan Chan, Wai Keung Leung, Tetsuya Goto, Yuen-Shan Ho, Raymond Chuen-Chung Chang
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:https://doi.org/10.1186/s12974-023-02747-4