Real-time visualization of oxidative stress-mediated neurodegeneration of individual spinal motor neurons in vivo

Generation of reactive oxygen species (ROS) has been shown to be important for many physiological processes, ranging from cell differentiation to apoptosis. With the development of the genetically encoded photosensitiser KillerRed (KR) it is now possible to efficiently produce ROS dose-dependently i...

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Bibliographic Details
Main Authors: Isabel Formella, Adam J. Svahn, Rowan A.W. Radford, Emily K. Don, Nicholas J. Cole, Alison Hogan, Albert Lee, Roger S. Chung, Marco Morsch
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718305974