Molecular fragment characteristics and distribution of tangle associated TDP-43 (TATs) and other TDP-43 lesions in Alzheimer’s disease

Molecular fragment characteristics and distribution of tangle associated TDP-43 (TATs) and other TDP-43 lesions in Alzheimer’s disease

TAR DNA binding protein 43 (TDP-43) pathology is a defining feature of frontotemporal lobar degeneration (FTLD). In FTLD-TDP there is a moderate-to-high burden of morphologically distinctive TDP-43 immunoreactive inclusions distributed throughout the brain. In Alzheimer’s disease (AD), similar TDP-...

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Bibliographic Details
Main Authors: Keith Anthony Josephs, Shunsuke Koga, Nirubol Tosakulwong, Stephen D. Weigand, Nha Trang Thu Pham, Matt Baker, Jennifer L. Whitwell, Rosa Rademakers, Leonard Petrucelli, Dennis W. Dickson
Format: Article
Language:English
Published: University of Münster / Open Journals System 2023-12-01
Series:Free Neuropathology
Subjects:
TAR DNA binding protein 43
TMEM106b
Cluster analysis
TAT
Hippocampal sclerosis
Online Access:https://www.uni-muenster.de/Ejournals/index.php/fnp/article/view/5192

Internet

https://www.uni-muenster.de/Ejournals/index.php/fnp/article/view/5192

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