Oxidative Defect Detection Within Free and Packed DNA Systems: A Quantum Mechanical/Molecular Mechanics (QM/ MM) Approach

Oxidative Defect Detection Within Free and Packed DNA Systems: A Quantum Mechanical/Molecular Mechanics (QM/ MM) Approach

Base excision repair enzymes (BERs) detect and repair oxidative DNA damage with efficacy despite the small size of the defects and their often only minor structural impact. A charge transfer (CT) model for rapid scanning of DNA stretches has been evoked to explain the high detection rate in the face...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Sophia Johnson, Ursula Rothlisberger
Format: Article
Sprog:deu
Udgivet: Swiss Chemical Society 2024-04-01
Serier:CHIMIA
Fag:
Chromatin
DNA
Molecular dynamics
Oxidative damage
QM/MM
Online adgang:https://www.chimia.ch/chimia/article/view/7248

Internet

https://www.chimia.ch/chimia/article/view/7248

Lignende værker