Oxidative Defect Detection Within Free and Packed DNA Systems: A Quantum Mechanical/Molecular Mechanics (QM/ MM) Approach

Oxidative Defect Detection Within Free and Packed DNA Systems: A Quantum Mechanical/Molecular Mechanics (QM/ MM) Approach

Base excision repair enzymes (BERs) detect and repair oxidative DNA damage with efficacy despite the small size of the defects and their often only minor structural impact. A charge transfer (CT) model for rapid scanning of DNA stretches has been evoked to explain the high detection rate in the face...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Sophia Johnson, Ursula Rothlisberger
Format: Artykuł
Język:deu
Wydane: Swiss Chemical Society 2024-04-01
Seria:CHIMIA
Hasła przedmiotowe:
Chromatin
DNA
Molecular dynamics
Oxidative damage
QM/MM
Dostęp online:https://www.chimia.ch/chimia/article/view/7248

Internet

https://www.chimia.ch/chimia/article/view/7248

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