Identification of the shared hub gene signatures and molecular mechanisms between HIV-1 and pulmonary arterial hypertension

Identification of the shared hub gene signatures and molecular mechanisms between HIV-1 and pulmonary arterial hypertension

Abstract The close link between HIV-1 infection and the occurrence of pulmonary arterial hypertension (PAH). However, the underlying molecular mechanisms of their interrelation remain unclear. The microarray data of HIV-1 and PAH were downloaded from GEO database. We utilized WGCNA to identify share...

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Bibliographic Details
Main Authors: Huanzhuo Mai, Xing Yang, Yulan Xie, Jie Zhou, Yiru Wei, Tingyan Luo, Jing Yang, Ping Cui, Li Ye, Hao Liang, Jiegang Huang
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
HIV-1
Pulmonary arterial hypertension
Type I IFN
Hub genes
scRNA-seq
Online Access:https://doi.org/10.1038/s41598-024-55645-x

Internet

https://doi.org/10.1038/s41598-024-55645-x

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