Senescence-associated secretory phenotype constructed detrimental and beneficial subtypes and prognostic index for prostate cancer patients undergoing radical prostatectomy

Abstract Background Cellular senescence is growing in popularity in cancer. A dual function is played by the senescence-associated secretory phenotype (SASP) that senescent cells produce in the development of pro-inflammatory niches, tissue regeneration or destruction, senescence propagation, and ma...

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Bibliographic Details
Main Authors: Dechao Feng, Jie Wang, Dengxiong Li, Ruicheng Wu, Wuran Wei, Chi Zhang
Format: Article
Language:English
Published: Springer 2023-08-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-023-00777-1