Affinity Tag Coating Enables Reliable Detection of Antigen-Specific B Cells in Immunospot Assays

Affinity Tag Coating Enables Reliable Detection of Antigen-Specific B Cells in Immunospot Assays

Assessment of humoral immunity to SARS-CoV-2 and other infectious agents is typically restricted to detecting antigen-specific antibodies in the serum. Rarely does immune monitoring entail assessment of the memory B-cell compartment itself, although it is these cells that engage in secondary antibod...

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Bibliographic Details
Main Authors: Sebastian Köppert, Carla Wolf, Noémi Becza, Giuseppe A. Sautto, Fridolin Franke, Stefanie Kuerten, Ted M. Ross, Paul V. Lehmann, Greg A. Kirchenbaum
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
antibody-secreting cell
fluorospot
memory B cell
plasmablast
antigen coating
influenza
Online Access:https://www.mdpi.com/2073-4409/10/8/1843

Internet

https://www.mdpi.com/2073-4409/10/8/1843

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