Molecular Cloning, Expression and Purification of G-CSF Isoform D, an Alternative Splice Variant of Human G-CSF

Granulocyte colony-stimulating factor (G-CSF) is the major regulator of hemopoiesis and granulopoiesis. However, overexpression of G-CSF has been implicated in several important processes in tumor biology such as tumor growth, angiogenesis, and metastasis. Four different mRNA isoforms resulting from...

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Bibliographic Details
Main Authors: Fatemeh Sadat Toghraie, Mahsa Yazdanpanah-Samani, Elham Mahmoudi Maymand, Ahmad Hosseini, Amir Asgari, Amin Ramezani, Abbas Ghaderi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2019-08-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/2240