Characterization of H3.3K36M as a tool to study H3K36 methylation in cancer cells
Recurrent mutations at key lysine residues in the histone variant H3.3 are thought to play an etiologic role in the development of distinct subsets of pediatric gliomas and bone and cartilage cancers. H3.3K36M is one such mutation that was originally identified in chondroblastomas, and its expressio...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2017-11-01
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Series: | Epigenetics |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/15592294.2017.1377870 |