Case report: Uridine triacetate in the management of delayed onset 5-fluorouracil toxicity: A case report and review of literature

Case report: Uridine triacetate in the management of delayed onset 5-fluorouracil toxicity: A case report and review of literature

5-fluorouracil (5FU) and capecitabine are fluoropyrimidine anti-neoplastic drugs commonly used in the treatment of different types of cancer. Hereditary dihydropyrimdine deaminase (DPD), thymidylate synthase mutations and drug overdose may lead to life-threatening toxicities. Uridine triacetate (UTA...

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Bibliographic Details
Main Authors: Aasems Jacob, Janeesh Sekkath Veedu, Insija Selene, Rishi Raj, Lakshmi Kannan, Reema Patel
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
5-fluorouracil
capecitabine
chemotherapy
toxicity
uridine triacetate
dihydropyridine deaminase deficiency
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.977734/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.977734/full

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